Lymphedema-related angiogenic tumors and other malignancies.
Identifieur interne : 012B98 ( Main/Exploration ); précédent : 012B97; suivant : 012B99Lymphedema-related angiogenic tumors and other malignancies.
Auteurs : Robert Lee ; Karl M. Saardi ; Robert A. Schwartz [États-Unis]Source :
- Clinics in dermatology [ 1879-1131 ]
Descripteurs français
- KwdFr :
- MESH :
- immunologie : Hémangiosarcome, Lymphoedème, Tumeurs cutanées.
- Humains, Lymphoedème.
English descriptors
- KwdEn :
- MESH :
- complications : Lymphedema.
- immunology : Hemangiosarcoma, Lymphedema, Skin Neoplasms.
- Humans.
Abstract
Chronic lymphedema has a permissive effect with certain types of malignancies, particularly angiosarcomas, in what is known as Stewart-Treves syndrome. The presumed mechanism of this effect is an immunocompromised district of the affected area. Most other cutaneous malignancies have also been described in lymphedematous areas, including basal cell carcinoma, squamous cell carcinoma, melanoma, Kaposi sarcoma, Merkel cell carcinoma, and several cutaneous lymphomas. The occurrence of such malignancies suggests a more general immunosuppression within the skin. The formation of collateral lymphatic and vascular vessels in response to lymphedema produces an environment rich in growth factors, which may also play a role. In addition to infection and other general skin care issues, regions affected by lymphedema should be monitored for malignant changes not limited to angiosarcomas.
DOI: 10.1016/j.clindermatol.2014.04.008
PubMed: 25160102
Affiliations:
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Le document en format XML
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Saardi</name><affiliation><nlm:affiliation>Department of Dermatology, Rutgers University - New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey, 07103.</nlm:affiliation><wicri:noCountry code="subField">07103</wicri:noCountry></affiliation></author><author><name sortKey="Schwartz, Robert A" sort="Schwartz, Robert A" uniqKey="Schwartz R" first="Robert A" last="Schwartz">Robert A. Schwartz</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Rutgers University - New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey, 07103. Electronic address: roschwar@cal.berkeley.edu.</nlm:affiliation><country wicri:rule="url">États-Unis</country></affiliation></author></analytic><series><title level="j">Clinics in dermatology</title><idno type="eISSN">1879-1131</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Hemangiosarcoma (immunology)</term><term>Humans</term><term>Lymphedema (complications)</term><term>Lymphedema (immunology)</term><term>Skin Neoplasms (immunology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Humains</term><term>Hémangiosarcome (immunologie)</term><term>Lymphoedème ()</term><term>Lymphoedème (immunologie)</term><term>Tumeurs cutanées (immunologie)</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Hémangiosarcome</term><term>Lymphoedème</term><term>Tumeurs cutanées</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Hemangiosarcoma</term><term>Lymphedema</term><term>Skin Neoplasms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Humains</term><term>Lymphoedème</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Chronic lymphedema has a permissive effect with certain types of malignancies, particularly angiosarcomas, in what is known as Stewart-Treves syndrome. The presumed mechanism of this effect is an immunocompromised district of the affected area. Most other cutaneous malignancies have also been described in lymphedematous areas, including basal cell carcinoma, squamous cell carcinoma, melanoma, Kaposi sarcoma, Merkel cell carcinoma, and several cutaneous lymphomas. The occurrence of such malignancies suggests a more general immunosuppression within the skin. The formation of collateral lymphatic and vascular vessels in response to lymphedema produces an environment rich in growth factors, which may also play a role. In addition to infection and other general skin care issues, regions affected by lymphedema should be monitored for malignant changes not limited to angiosarcomas.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country></list><tree><noCountry><name sortKey="Lee, Robert" sort="Lee, Robert" uniqKey="Lee R" first="Robert" last="Lee">Robert Lee</name><name sortKey="Saardi, Karl M" sort="Saardi, Karl M" uniqKey="Saardi K" first="Karl M" last="Saardi">Karl M. Saardi</name></noCountry><country name="États-Unis"><noRegion><name sortKey="Schwartz, Robert A" sort="Schwartz, Robert A" uniqKey="Schwartz R" first="Robert A" last="Schwartz">Robert A. Schwartz</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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